Late-night radio-show psychologist Rain Sommers is used to the crazies who call in to rage from the back alleys of the French Quarter and the shadows of the bayou. But one caller's chilling obsession with her and her long-ago murdered mother—an iconic singer beloved among the city's Goth community—has even the jaded Rain running scared as a sadistic serial killer known as the Vampire prowls New Orleans.

FBI agent Trevor Rivette is convinced her midnight caller and the killer are one and the same. As it becomes disturbingly clear that the Vampire has a sick bloodlust only Rain can satisfy, she allows Trevor to get closer and closer. But he soon discovers that his secretive past and troubled present are intertwined—and that he may die trying to keep Rain's fate out of a madman's control.